"Differential Motion Dynamics of Synaptic Vesicles Undergoing Spontaneous and Activity-Evoked Endocytosis"
Amy Peng, Ziv Rotman, Pan-Yue Deng and Vitaly A. Klyachko NEURON 73:1108-1115, 2012.
Synopsis: The authors use nanometer-resolution imaging to examine the dynamic properties of synaptic vesicles in central neurons, with the focus on vesicles supporting two fundamental forms of neurotransmission, the spontaneous and activity-evoked ones. The study demonstrates that the vesicles involved in these two forms of neurotransmission differ in dynamic behavior, particularly in the ability to engage in motor-mediated transport.Following is the link to the paper: http://www.cell.com/neuron/abstract/S0896-6273(12)00141-9
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